BoneNET: a network model of bone microstructure and dynamics

نویسندگان

  • Taehyong Kim
  • Lawrence Bone
  • Murali Ramanathan
  • Aidong Zhang
چکیده

We develop a network model of bone microstructure and dynamics, BoneNET, which is capable of quantitative assessment of Bone Mineral Density (BMD) and bone remodelling dynamics. First, we introduce a network model of bone microstructure by describing structural properties and process of bone network modelling. Secondly, we explain a mathematical model of bone microstructure by analysing the density for mineralised fibres of bone microstructure. Finally, we provide a bone remodelling dynamics among osteoblast and osteoclast and study bone networks by proposing several measurements to calculate bone strength and identify critical elements in bone microstructure.

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عنوان ژورنال:
  • International journal of data mining and bioinformatics

دوره 8 2  شماره 

صفحات  -

تاریخ انتشار 2013